National Center for Spinal Disorders/ Buda Health Center

Full name of member institute/department or working group:
National Center for Spinal Disorders/ Buda Health Center
Address: 1126 Budapest, Királyhágó u. 1-3.

Dr. Varga Péter Pál, chief executive officer of Buda Health Center
dr. Hoffer Zoltán, director of National Center for Spinal Disorders
dr. Somhegyi Annamária Ph.D., director for prevention at National Center for Spinal Disorders
dr. Lazáry Áron Ph.D., director for research at National Center for Spinal Disorders
Leader’s contact:;;;

Description of the activities of the member institution as follows:
-    Main profile of the hospital is surgical and non-surgical treatment of degenerative spinal disorders as well as primary and secondary prevention.
-    Research area covers the development of surgical techniques and mapping of the genetical background of degenerative spinal disorders and tumors. Apart of the clinical follow up studies an in silico biomechanical laboratory was founded in the National Center for Spinal Disorders.
-    The hospital gives home to the Semmelweis University Orthopedic Department Spinal Care Unit which is involved with the orthopedic training of medical students.
-    Postgraduate and internal courses are regularly organized for doctors and other medical professions.
-    The primary prevention program of the Hungarian Spine Society started in 1995 is working from the very beginning in collaboration with the National Center for Spinal Diseases, and also professional symposia and conferences are regularly organized together.   
-    Professional activates carried out in the hospital are in the field of clinical and research of spinal disorders.

Publications (2017-)
Bettegowda, C., et al., Spinal column chordoma: prognostic significance of clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival. Neuro Oncol, 2017. 19(3): p. 405-413.
Stacchiotti, S., et al., Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group. Ann Oncol, 2017. 28(6): p. 1230-1242.
Szendroi, M., et al., Diagnostic algorithm, prognostic factors and surgical treatment of metastatic cancer diseases of the long bones and spine. EFORT Open Rev, 2017. 2(9): p. 372-381.
Fortin M, Lazáry À, Varga PP, Battié MC. Association between paraspinal muscle morphology, clinical symptoms and functional status in patients with lumbar spinal stenosis. Eur Spine J. 2017 Oct;26(10):2543-2551. doi: 10.1007/s00586-017-5228-y. Epub 2017 Jul 26.
Versteeg AL, Dea N, Boriani S, Varga PP, Luzzati A, Fehlings MG, Bilsky MH, Rhines LD, Reynolds JJ, Dekutoski MB, Gokaslan ZL, Germscheid NM, Fisher CG. Surgical management of spinal osteoblastomas. J Neurosurg Spine. 2017 Sep;27(3):321-327. doi: 10.3171/2017.1.SPINE16788. Epub 2017 Jul
Quraishi NA, Boriani S, Sabou S, Varga PP, Luzzati A, Gokaslan ZL, Fehlings MG, Fisher CG, Dekutoski MB, Rhines LD, Reynolds JJ, Germscheid NM, Bettegowda C, Williams RP. A multicenter cohort study of spinal osteoid osteomas: results of surgical treatment and analysis of local recurrence. Spine J. 2017 Mar;17(3):401-408. doi: 10.1016/j.spinee.2016.10.010. Epub 2016 Oct 17.
Charest-Morin R, Fisher CG, Varga PP, Gokaslan ZL, Rhines LD, Reynolds JJ, Dekutoski MB, Quraishi NA, Bilsky MH, Fehlings MG, Chou D, Germscheid NM, Luzzati A, Boriani S; AOSpine Knowledge Forum Tumor. En Bloc Resection Versus Intralesional Surgery in the Treatment of Giant Cell Tumor of the Spine. Spine (Phila Pa 1976). 2017 Sep 15;42(18):1383-1390.
Lazáry Á, Szövérfi Z, Varga PP. [Change of paradigm in the surgical treatment of metastatic diseases of the bone. Part II. Treatment of spinal metastases]. Orv Hetil. 2018 Feb;159(8):297-302. doi: 10.1556/650.2018.30930.
Szita J, Boja S, Szilagyi A, Somhegyi A, Varga PP, Lazary A. Risk factors of non-specific spinal pain in childhood. Eur Spine J. 2018 May;27(5):1119-1126. doi: 10.1007/s00586-018-5516-1. Epub 2018 Feb 15.
Versteeg, A.L., et al., Psychometric evaluation and adaptation of the Spine Oncology Study Group Outcomes Questionnaire to evaluate health-related quality of life in patients with spinal metastases. Cancer, 2018. 124(8): p. 1828-1838.
Dea N, Fisher CG, Reynolds JJ, Schwab JH, Rhines LD, Gokaslan ZL, Bettegowda C, Sahgal A, Lazáry Á, Luzzati A, Boriani S, Gasbarrini A, Laufer I, Charest-Morin R, Wei F, Teixeira W, Germscheid NM, Hornicek FJ, DeLaney TF, Shin JH; AOSpine Knowledge Forum Tumor. Current treatment strategy for newly diagnosed chordoma of the mobile spine and sacrum: results of an international survey. J Neurosurg Spine. 2018 Oct 19;30(1):119-125.
Charest-Morin R, Dirks MS, Patel S, Boriani S, Luzzati A, Fehlings MG, Fisher CG, Dekutoski MB, Williams R, Quraishi NA, Gokaslan ZL, Bettegowda C, Germscheid NM, Varga PP, Rhines LD; AOSpine Knowledge Forum Tumor. Ewing Sarcoma of the Spine: Prognostic Variables for Survival and Local Control in Surgically Treated Patients. Spine (Phila Pa 1976). 2018 May 1;43(9):622-629.
Charest-Morin R, Fisher CG, Versteeg AL, Sahgal A, Varga PP, Sciubba DM, Schuster JM, Weber MH, Clarke MJ, Rhines LD, Boriani S, Bettegowda C, Fehlings MG, Arnold PM, Gokaslan ZL, Dea N. Clinical presentation, management and outcomes of sacral metastases: a multicenter, retrospective cohort study. Ann Transl Med. 2019 May;7(10):214.
Bettegowda, C., et al., Prognostic significance of hTERT (human telomerase reverse transcriptase) promoter region mutations C228T and C250T for overall survival in spinal chordomas. Neuro Oncol, 2019.
Kiss L, Varga PP, Szoverfi Z, Jakab G, Eltes PE, Lazary A. Indirect foraminal decompression and improvement in the lumbar alignment after percutaneous cement discoplasty. Eur Spine J. 2019 Jun;28(6):1441-1447. doi: 10.1007/s00586-019-05966-7. Epub 2019 Apr 20.
Éltes PE , Kiss L , Bartos M , Eösze Z , Szövérfi Z , Varga PP , Lazáry Á . Attitude of spine surgeons towards the application of 3D technologies - a survey of AOSpine members. Ideggyogy Sz. 2019 Jul 30;72(7-8):227-235. doi: 10.18071/isz.72.0227.
Costa MC, Eltes P, Lazary A, Varga PP, Viceconti M, Dall'Ara E. Biomechanical assessment of vertebrae with lytic metastases with subject-specific finite element models. J Mech Behav Biomed Mater. 2019 Oct;98:268-290. doi: 10.1016/j.jmbbm.2019.06.027. Epub 2019 Jun 29.
Biczo A, Szita J, McCall I, Varga PP; Genodisc Consortium, Lazary A. Association of vitamin D receptor gene polymorphisms with disc degeneration. Eur Spine J. 2020 Mar;29(3):596-604. doi: 10.1007/s00586-019-06215-7. Epub 2019 Nov 25.

Dr. Somhegyi Annamária Ph.D., director for prevention
1126 Budapest, Királyhágó utca 1-3,
E-mail:; Phone: +36302025317

The most important news, events and results of the last two years:

-    Annamária Somhegyi has participated in the strategy development of the National Public Health Program „Az ifjúság egészségfejlesztése” (“Youth health promotion”) and „Mozgásszervi betegségek megelőzése”(„Prevention of Musculoskeletal Diseases”).
-    Annamária Somhegyi took part in the conceptualization of the National Musculoskeletal Program (with prof. Dr. Poór Gyula) and the National Pediatric Health Program (with dr. Fekete Ferenc).
-    In 2018 Annamária Somhegyi was elected by the EMMI as the Hungarian national coordinator for the WHO „Schools for Europe Network Foundation” (SHE).
-    Annamária Somhegyi participated in the posture correction training modules organized by the Pedagogy Educational Centers.
-    One major focus of the research and development department was to enhance the quality of the Hungarian spinal research by cross culturally adapting and validating international gold standard patient reported outcome measurement tools into Hungarian language.

-    Annamária Somhegyi initiated and actively collaborated with the Penalty Enforcement Holding/Ministry for Home Affairs, a company taking part in manufacturing school furniture, for redesigning and resizing of school chairs in order to have a better spine protection for the students.
-    Annamária Somhegyi participated in the posture correction training modules organized by the Pedagogy Educational Centers.
-    Annamária Somhegyi participated in the SHE coordinated evaluation of the European school-based health promotion.
-    Annamária Somhegyi participated in the renewal of the SHE Manual for schools.
-    State-secretary Dr. Ildikó Horváth (Ministry of Human Capacities, Health Department) fully authorized Annamária Somhegyi to work for the holistic health promotion (HHP) in educational institutions in the name of the Health Department.
-    Annamária Somhegyi has started a series of articles in the SHE Newsletter to show the work for HHP in the Hungarian schools.  
-    Semmelweis University Orthopedic Department Spinal Care Unit was founded in the National Center for Spinal Disorders with Áron Lazáry as head of the unit.

-    Annamária Somhegyi shared her suggestions with the State Secretariat Responsible for Public Education (Ministry of Human Capacities) to make some corrections in the renewed national physical education curriculum and in the re-formulation of competencies for physical education teachers: she advised to include the special posture correction exercises more accurately - in order to achieve and automatize the biomechanically correct posture for school children.
-    Annamária Somhegyi collaborated with the Ministry of Human Capacities in organizing  a nationwide online study to follow up the implementation of HHP in the Hungarian schools, which was realized in February 2020.  
-    On 16th March 2020 - when the homeschooling system started in Hungary according to the COVID19 pandemic - the Hungarian Public Service Media started to broadcast a new series of teaching/learning programme to help teachers and school children in their digital teaching/learning on the National Television. On 17th March 2020. Annamária Somhegyi has launched a cooperation with the Hungarian Public Service Media to create and insert a new and special series of physical exercises into the teaching and learning programme of the National Television – so that children and their parents can participate in exercises without straining their spine and joints. As a result, the daily TV program called “Move at home!” (Mozogj otthon!) was created and broadcasted several times a day from 8th April until mid-august (with 130 episodes). The program was recognized and recommended by international forums such as the WHO SHE, the WHO HEPA and the EU OSHA.
-    Annamária Somhegyi actively participates in the work of the SHE: in renewing the regular evaluation and the standards and indicators applied for the measurement.
-    Professional postgraduate courses and laymen health development and prevention events are held in the newly established BEK Academy.
-    As a result of the changes in the clinical settings caused by COVID-19 pandemic the follow up study protocols and clinical registries were digitalized and modernized.

Important websites where many materials and videos are available for all:

Spinal prevention: (informations also in English)
Holistic health promotion (HHP) in schools: (informations also in English)